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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRK1
All Species:
17.27
Human Site:
Y95
Identified Species:
31.67
UniProt:
Q15835
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15835
NP_002920.1
563
63526
Y95
L
W
K
D
I
E
D
Y
D
T
A
D
N
D
L
Chimpanzee
Pan troglodytes
XP_001152241
531
61192
Y90
F
L
D
A
V
A
E
Y
E
V
A
D
D
E
D
Rhesus Macaque
Macaca mulatta
XP_001105738
328
37461
Dog
Lupus familis
XP_542675
460
51324
R70
S
E
Q
P
I
G
K
R
L
F
Q
Q
F
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVL4
564
63818
Y95
L
W
K
D
I
E
D
Y
D
T
A
D
D
D
L
Rat
Rattus norvegicus
Q63651
564
63750
Y95
L
W
K
D
I
E
D
Y
D
T
A
D
D
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514822
565
64022
Y95
L
W
E
A
I
E
D
Y
D
T
A
A
D
E
F
Chicken
Gallus gallus
NP_990026
593
64642
F128
L
W
E
E
L
E
A
F
E
C
C
E
E
G
E
Frog
Xenopus laevis
NP_001087513
575
66421
Y90
F
L
D
A
V
V
E
Y
E
V
S
P
D
E
K
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
L44
L
N
D
F
I
Q
K
L
S
A
N
S
Y
A
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32866
714
80668
F110
G
H
D
I
G
R
R
F
L
D
V
E
A
Q
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09537
642
73759
L103
D
G
Q
S
R
R
D
L
A
S
S
I
V
S
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11792
824
91793
N321
G
S
S
N
G
P
K
N
D
S
S
H
P
I
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.3
56.4
70.6
N.A.
85.6
86.1
N.A.
77.8
55.3
45
28.9
N.A.
37.5
N.A.
41.9
N.A.
Protein Similarity:
100
64.1
57.7
76
N.A.
94.1
94.1
N.A.
90
68.4
66.2
45.8
N.A.
52.6
N.A.
59
N.A.
P-Site Identity:
100
20
0
6.6
N.A.
93.3
93.3
N.A.
60
20
6.6
13.3
N.A.
6.6
N.A.
13.3
N.A.
P-Site Similarity:
100
53.3
0
13.3
N.A.
100
100
N.A.
80
60
46.6
20
N.A.
20
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
24
0
8
8
0
8
8
39
8
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
8
% C
% Asp:
8
0
31
24
0
0
39
0
39
8
0
31
39
24
8
% D
% Glu:
0
8
16
8
0
39
16
0
24
0
0
16
8
24
8
% E
% Phe:
16
0
0
8
0
0
0
16
0
8
0
0
8
0
8
% F
% Gly:
16
8
0
0
16
8
0
0
0
0
0
0
0
8
8
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
8
47
0
0
0
0
0
0
8
0
8
0
% I
% Lys:
0
0
24
0
0
0
24
0
0
0
0
0
0
0
8
% K
% Leu:
47
16
0
0
8
0
0
16
16
0
0
0
0
8
39
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
0
0
0
8
0
0
8
0
8
0
0
% N
% Pro:
0
0
0
8
0
8
0
0
0
0
0
8
8
0
0
% P
% Gln:
0
0
16
0
0
8
0
0
0
0
8
8
0
8
0
% Q
% Arg:
0
0
0
0
8
16
8
8
0
0
0
0
0
0
0
% R
% Ser:
8
8
8
8
0
0
0
0
8
16
24
8
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
31
0
0
0
0
0
% T
% Val:
0
0
0
0
16
8
0
0
0
16
8
0
8
0
0
% V
% Trp:
0
39
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
47
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _